Probably this is the first time , I am starting a new post before I complete a post which I have already started , and is incomplete.
Baaad Capt Ajit Vadakayil !
Well this post would have been a usual answer to a query in the comments column.
But then I realized that this problem of Uric acid in the human body has now become an epidemic.
Modern doctors and evil pharma are minting money.
They do NOT want you to be wise.
You could stand on the roadside of a city in US and count the people as they walk past ( men only ). Out of every 20 men who walk past, one is suffering from problems with Uric acid , usually Gout.
So what does our quintessential Hilly Billy yank do?
He goes running to a doctor— who prescribes evil pharma’s medicines –to bring down the level of uric acid.
Well Uric acid has to be kept in balance –like what we do in Ayurveda — mostly by controlling the diet and balancing the Tamas Rajas .
If the medicines of evil pharma keeps the Uric acid level too low—then you become senile fast. And get these fancy modern rich man’s diseases like Alzheimer’s and Parkinson’s disease..
Now this disease has come to India, thanks to the soft drinks they consume like Coke and Pepsi, containing high fructose sugar .
I had posted on this subject—but then I realized that because the post was getting too long, I had ignored the Uric acid bit, just given a passing mention in one single sentence.
Punch into Google search-
HIGH FRUCTOSE CORN SYRUP, FATTY LIVER DISEASE, DIABETES VADAKAYIL
and
FATHERS OF SURGERY AND MEDICINE 4200 BC VADAKAYIL
Nowadays I get to watch the MASTER CHEF contest.
Below: Why is the dish screwed up ? Errr, I innovated !-- WOW ! You have balls of steel !!!
Below: Why is the dish screwed up ? Errr, I innovated !-- WOW ! You have balls of steel !!!
People who have eaten nothing more than meat and potatoes – are now trying to prove that they eat the best and the VASTESTESTEST variety of food on the planet—so guys--eat your hearts out !.
Only thing is that all of them dishes pushes them towards gout.
Hey, how about healthy cookin’ ?
WE HAVE ALREADY EATEN OUR MANGY HEARTS OUT , AND WE ARE 100% CONVINCED NOW, THAT EVEN DURING THE STONE AGE YOU ATE ALL THIS FANCY ARTY STUFF !
Hyperuricemia is an excess of uric acid in the blood. Uric acid passes through the liver, and enters the bloodstream.
Purines are nitrogen-containing compounds, which are made inside the cells of your body (endogenous).
Or it comes from outside of your body, from intake of foods containing purine (exogenous). Purines are components of nucleosides, the building blocks of DNA and RNA.
This is why fermented beer is very bad.
Purine breaks down into uric acid. Increased levels of uric acid from excess purines may accumulate in your tissues, and form crystals. This may cause high uric acid levels in the blood.
Purines are abundant in meats.
Excess purine nucleosides are removed from the body by breakdown in the liver and excretion from the kidneys.
When uric acid levels build up and become high, there is an increased risk of developing kidney problems and arthritis . Some of the most common forms of arthritis are osteoarthritis, rheumatoid arthritis, and gout.
Osteoarthritis is the most common.. It is a degenerative joint disease that frequently develops following trauma or infection of a joint, and it can also occur as a result of aging.
Rheumatoid arthritis is an autoimmune disease in which the body’s immune system starts attacking its own tissues.
Gout is the most painful form of arthritis. Deposits of uric acid crystals in the joints cause redness, inflammation, and intense pain. Most experience their first gout attack in the big toe, or the metatarsophalangeal joint of the big toe.
King Henry of England had terrible Gout.
Punch into Google search-
MARY MARY QUITE CONTRARY, THE BLOODY MARY VADAKAYIL
I have heard a Olympic champion say on TV, 25 years ago, that they usually piss into the swimming pool while training. Piss combined with chlorine in water aint no good. Chlorination is used primarily to prevent pathogenic microorganisms from growing. The disinfection byproducts include cyanogen chloride (CNCl) and trichloramine (NCl3).
Cyanogen chloride is a toxic compound that affects many organs, including the lungs, heart and central nervous system by inhalation. Uric acid from piss is "an efficient precursor to the formation of CNCl and NCl3.
Mind it !
Other joints such as the ankles, wrists, fingers, or elbows may be affected. The pain can be so intense that even the pressure of a light bed sheets cover may be unbearable.
Often, the attack wakes a person from sleep. The toe is very sore, red, warm, and swollen. Attacks often begin in the early morning reach a peak within 6 to 24 hours. Even without treatment, the attacks typically subside spontaneously within several days to two weeks.
Acute gout attacks can also be accompanied by high fever and leukocytosis (elevated white blood cell count.
Deposits of uric acid (called tophi) look like lumps under the skin.
Uric acid levels can be measured by a blood test. Uric acid formation may occur when the blood uric acid level rises above 7 mg/dL. High uric acid levels can be caused by medical disorders like diabetes, kidney stones, kidney disease, and certain blood disorders.
When you have a kidney disease, it is not be able to clear the uric acid out of your system, thus causing hyperuricemia.
There are some medications that can cause increased levels of uric acid. These include aspirin, diuretics, vitamin C, caffeine etc .
Uric acid levels are controlled by the rate of uric acid production ( synthesis in the liver ) and the rate of uric acid excretion via kidneys .
Excretion has the greatest effect on blood uric acid levels, with about 90% of hyperuricemia cases attributed to impaired renal excretion.
Though it is termed as a "waste product" of purine metabolism, only about 10% of the uric acid that enters a normal human kidney is excreted from the body. A healthy kidney returns up to 90% of it to the blood stream.
Uric acid as one of the most important antioxidants in body fluids, responsible for the neutralization of over 50% of the free radicals in the blood stream.
This is what ( 85 lakh donation party) modern doctors do NOT understand. Like vitamin C, uric acid has a major role in protecting high-oxygen tissues (like the brain) from damage.
Below : Women suffer less from Gout than men. See the women's lib is now one up above men,when it comes to scoring brownie points
They must watch the " women's power " video below. THESE PERVERTED MEN MUST CHANGE THEIR MINDSETS !
Below : Women suffer less from Gout than men. See the women's lib is now one up above men,when it comes to scoring brownie points
They must watch the " women's power " video below. THESE PERVERTED MEN MUST CHANGE THEIR MINDSETS !
ARNAB GOSWAMI WANTS THE 3 MEN IN THE VIDEO ABOVE, TO BE JAILED FOR EVE TEASING !
Gout is more common in overweight people and the risk of gout attacks increases with higher body weights. Overweight persons must lose weight but gradually. Sudden weight loss can act in contradiction by increasing uric acid levels. So, avoid crash dieting.
IF YOU WANT MEN TO CHANGE THEIR MINDSETS --PUNCH INTO GOOGLE SEARCH!
Above: mE lungi mE right !! mE family jewels, mE right !!
Hyperuricemia and gout are both risk factors for kidney or bladder stones (urolithiasis). Both conditions increase the risk of forming not only uric acid stones, but also the more common calcium oxalate stones. The presence of calcium oxalate stones is 10-30 times higher in gout patients than those without gout. Prior to the development of uric acid lowering treatments, kidney disease occurred in up to 40% of gout patients; renal failure was the usual cause of death in 25% of these patients.
Levels of uric acid may increase in the blood if a patient has kidney damage leading to poor excretion of uric acid, or if there is an over production of uric acid in the blood due to ingestion of excessive purine-rich foods.
Creatinine level will not increase until about 45-50% of kidney function is lost as our kidneys have very strong compensatory ability. High creatinine and high uric acid levels are two symptoms of kidney disease.
The urine carries salts, including calcium oxalate, uric acid, cystine, or xanthine. These salts can become extremely concentrated if there is not enough urine, or if unusually high amounts of crystal-forming salts are present.
This is why it is important to drink water. Alcohol dehydrates your body.
Normally, urine contains substances that may protect against stone formation, including:
Magnesium
Citrate
Pyrophosphate
Enzymes
These substances allow salt in the urine to be at higher-than-normal concentrations without forming crystals . They prevent crystal formation - coat the crystals and prevent them from sticking to the surface of kidney tubes Not having enough of these protective substances can cause stones. .
Changes in the acid balance of the urine can affect stone formation. Uric acid and cystine stones mainly form in acidic urine. Calcium phosphate and struvite stones increase in alkaline urine. This is why things have to be in balance.
HFCS used as a sweetener in soft drinks , promotes a rise in uric acid levels in your bloodstream.
Primary hyperoxaluria is an inherited disorder in which too much oxalate in the urine is the main problem.
Secondary hyperoxaluria results from specific conditions that cause high levels of urinary oxalate.
Secondary hyperoxaluria is usually caused by too much dietary oxalates (found in a number of common vegetables, fruits, and grains) or by problems in the body's breakdown of oxalates.
Such defects may be due to various factors:
Severe vitamin B6 deficiencies (usually due to genetic disorders)
Deficiencies in intestinal flora bacteria that breaks down oxalate
Inability of small intestine to properly absorb fat and nutrients. Calcium may bind to the unabsorbed fat instead of the oxalates, which causes a buildup of oxalate
Female hormones (estrogens) actually lower the risk of hyperoxaluria. Estrogen may help prevent the formation of calcium oxalate stones by keeping urine alkaline, and raising protective citrate levels. This is why men get gout more than women .
Women’s lib party—please note down in your diaries. Read it out when you wanna score brownie points-- but make sure you drop them coins ! TEE HEEEE !!.
Since uric acid comes from the breakdown of purines, and, purines also exist in our foods, a gout sufferer needs to go onto a diet that is relatively low in purines in order to lessen uric acid levels. This also means avoiding high purine foods completely...
Foods that are high in purine include:
All organ meats (such as liver/ kidney ).
Yeasts, and yeast extracts (such as beer, and alcoholic beverages)
Asparagus, spinach, beans, peas, lentils, oatmeal, cauliflower and mushrooms.
Foods that are high in animal protein , red meat , shell fish, prawns , pork, beef and egg yolk.
Foods high on fat- refined bread, biscuits, muffins, cakes
Dairy products like cheese, curd.
Coffee
Excessive salt, oily and hot foods.
Alcohol increases purine catabolism in the liver and increases the formation of lactic acid which blocks urate secretion by the renal tubules. Excessive alcohol consumption can have severe negative effects in the ability of the kidneys to maintain the body’s fluid, electrolyte, and acid-base balance.
In acid urine of pH less than 5.5, uric acid crystals precipitate and lead to stone formation. Alkalinization is accomplished by drinking a solution of half a teaspoon of baking soda (sodium bicarbonate, NaHCO3) dissolved in a glass of water.
If you have a sodium restricted diet, this should be done under a doctor’s supervision since each half teaspoon of baking soda has 616 mg of sodium. Sodium may be eliminated by using potassium bicarbonate instead of baking soda.
Warming the affected joints increase the solubility of monosodium urate crystals. Warming the joints may be accomplished with a foot bath or a heating pad. Hydration requires increasing the volume of drinking water to promote more frequent urination. Drink eight glasses of water per day or 3 litres of water. Avoid diuretic medications.
Foods that are low in purine include:
Refined cereals - breads, pasta, flour, cakes
Milk and milk products, eggs whites
Lettuce, tomatoes, green vegetables, Bitter gourd, Papaya
Lime juice without white processed sugar ( use honey ).
Fruits.
Too much uric acid production can be taxing on the kidneys. The human kidney is a master Tamas Sattwa Rajas ( Brahma/ Vishnu/ Shiva ) balancer as it ensures the right balance between uric acid that is needed for different bodily processes and left over uric acid that needs to dealt with.
When too much uric acid is taken in, the kidneys process what is needed and then use the excess uric acid to form crystals. These crystals are then deposited into natural storage areas in our bodies.
Unfortunately for humans, these storage areas are in various joints like elbows and knees, or far off appendages like toes. When too many of these crystals build up in these areas they cause inflammation , unbearable pain and swelling.
Keep your body well hydrated, drinking upto 3 liters of water per day, unless you were told otherwise. Do NOT hydrate with beer as despite having less alcohol per serving than the other beverages, is more hyperuricemic due to its high purine content .
Treatments for gout are not very effective and have undesirable side effects. The most common treatments include the administration of nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen. Aspirin is not used because it aggravates hyperuricemia by increasing uric acid retention. Side effects of medications can cause stomach pain, bleeding and ulcers, and beyond a certain dosage, they do not provide additional relief.
Corticosteroids, such as prednisone, are prescribed for severe cases of gout. Although these steroids can provide relief, they also have serious side effects, including thinning bones, poor wound healing, and a weakened immune system. Cortisone injections into an affected joint are generally limited to no more than three per year because of the side effects.
Allopurinol, probenecid, and colchicine are sometimes prescribed in daily doses to reduce the risk or lessen the severity of future episodes. Allopurinol blocks the formation of uric acid, probenecid decreases the frequency of attacks of gout by increasing the kidney’s excretion of uric acid, and colchicine may relieve swelling and help prevent the frequency of gout attacks.
The above para is just for information and NOT to do self medication. Rely only on doctor’s advise.
These drugs speed the elimination of uric acid from the body, and they also slow down the rate at which it is produced, but they may cause nausea or skin rashes as side effects.
Gout patients had increased incidence of all types of cancer, including cancers of the oral cavity, pharynx, colon, liver and biliary tract, pancreas, lung, skin (melanoma and nonmelanoma), endometrium and kidney, as well as of malignant melanoma.
DNA and RNA are called nucleic acids because they reside in the nucleus of the cells. Uric acid is produced from the oxidation of adenine and guanine in these nucleic acids. Milk contains no purines because it consists of fats, casein and whey proteins, but no cell nuclei. Fermented milk products, such as yogurt and aged cheeses, have purines from the nucleic acids of the bacterial cells that proliferate during fermentation.
We in Kerala never had gout. Now, our hospitals are full of gout party ,mostly Muslims and Christians who eat beef and offal . Of course all drink soft drinks like Coke with HFCS. Any young man who drinks two cans of Coke a day are 97 percent more likely to develop the disease, as per US surveys.
The Hindu method of fasting and breaking fast with foods of low purine content , meals loaded with Turmeric/ Garlic / Spices kept them away from gout.
A gout attack can be brought on by stressful events—so be a cool cat !
CAPT AJIT VADAKAYIL
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