WORDPRESS POLLS CONSOLIDATED , PART 4- CAPT AJIT VADAKAYIL

THIS POST IS CONTINUED FROM PART 3, BELOW--

https://ajitvadakayil.blogspot.com/2021/09/wordpress-polls-consolidated-part-3.html

https://captajitvadakayil.in/2022/01/23/vadakayil-says-useless-and-dangerous-mrna-vaccines-devastates-the-human-body-and-mind-for-several-generations-poll/

Vaccines for SARS, MERS and RSV have never been approved ..  There is serious mechanistic concern: that vaccines designed empirically using the traditional approach (consisting of the unmodified or minimally modified coronavirus viral spike to elicit neutralizing antibodies), be they composed of protein, viral vector, DNA or RNA and irrespective of delivery method,  worsenS COVID-19 disease via antibody-dependent enhancement (ADE )..  In ADE the covid vaccine actually enhances the virus' ability to enter and infect your cells, resulting in more severe disease than had you not been vaccinated. ..  This is the exact opposite of what a vaccine is supposed to ..  …#####    https://captajitvadakayil.in/2021/07/31/vadakayil-on-pfizers-chicken-coming-home-to-roost-ade-antibody-dependant-enhancement-trojan-horse-pathway-poll/   ####..  The ADE of virus infection is a phenomenon in which virus-specific antibodies enhance the entry of virus, and in some cases the replication of virus, into monocytes/macrophages and granulocytic cells through interaction with Fc and/or complement receptors.   . These viruses share some common features such as preferential replication in macrophages, ability to establish persistence, and antigenic diversity. ..   when they tried to develop an RSV vaccine in the 1960s. RSV is an upper respiratory illness that is very similar to that caused by coronaviruses. At that time, these criminals had decided to skip animal trials and go directly to human trials of third world nations using them as guinea pigs. .   ####   https://captajitvadakayil.in/2021/08/10/vadakayil-on-bribed-honey-trapped-virologists-in-jewish-vaccine-lobby-payroll-working-within-who-us-cdc-nih-icmr-deliberately-off-loading-rsv-respiratory-syncytial-virus-as-sars-cov-2-virus/   ####...   The children were exposed to the wild virus, they all became sick. Several of them died. They abandoned the vaccine. It was a big embarrassment to FDA and NIH. ..  Coronaviruses produce not just one but two different types of antibodies:---- Neutralizing antibodies, also referred to as immunoglobulin G (IgG) antibodies, that fight the infection ..  Binding antibodies (also known as non-neutralizing antibodies) that cannot prevent viral infection ..  Instead of preventing viral infection, binding antibodies trigger an abnormal immune response known as "paradoxical immune enhancement." Another way to look at this is your immune system is actually backfiring and not functioning to protect you but actually making you worse. ..  Many of the COVID-19 vaccines currently in the running are using mRNA to instruct your cells to make the SARS-CoV-2 spike protein (S protein). The spike protein, which is what attaches to the ACE2 receptor of the cell, is the first stage of the two-stage process viruses use to gain entry into cells. ..  , if the vaccine does not result in a robust response in neutralizing antibodies, you will be at risk for more severe lung disease if you're infected with the virus. ..  COVID-19 VACCINES ARE NOT DESIGNED TO PREVENT INFECTION.   SARS-CoV ADE is primarily mediated by diluted antibodies against envelope spike proteins rather than nucleocapsid proteins. monoclonal antibodies promoted SARS-CoV infection.  ####   https://captajitvadakayil.in/2022/01/20/vadakayil-on-why-maneka-gandhi-likes-stray-dogs-indians-used-as-guinea-pigs-for-useless-and-dangerous-monoclonal-antibodies-poll/   ####...  antibodies against SARS-CoV spike proteins trigger ADE effects.   COVID-19 vaccines end up making people more prone to severe SARS-CoV-2 infection.   showing the elderly — who are most vulnerable to severe COVID-19 — are also the most vulnerable to ADE. elderly COVID-19 patients have far higher levels of anti-spike antibodies — which, increase infectivity — than younger patients.  Immune enhancement of disease can  occur in two ways. Firstly, non-neutralizing or sub-neutralizing levels of antibodies can enhance SARS-CoV-2 infection into target cells.  Antibodies could enhance inflammation and hence severity of pulmonary disease ..  Vaccines that target other parts of the virus, such as the nucleocapsid, without the S protein, have shown no protection against CoV infection and increased lung pathology. immunization with S protein based CoV vaccines have displayed signs of enhanced lung pathology …   The choice of antigen target, vaccine efficacy and risk of immunopathology are dependent on other ancillary factors, including adjuvant formulation, age at vaccination ... and route of immunization. ..  : For ADE, immune complex internalization is mediated by the engagement of activating Fc receptors on the cell surface. Co-ligation of inhibitory receptors then results in the inhibition of antiviral responses  leads to increased viral replication. Antibodies cause immunopathology by activating the complement pathway or antibody-dependent cellular cytotoxicity (ADCC). For both pathways, excessive immune activation results in the release of cytokines and chemokines, leading to enhanced disease pathology.  The vaccines aren't even designed to prevent infection, only reduce the severity of symptoms which is bullshit ., they  make you sicker once you're exposed to the virus.   For immunocompromised patients, the regular two-dose COVID-19 vaccine regimen—and  even a third dose—didn't provide  immune protection at all—100%.  ..  When the vaccines came out, no one knew how immunocompromised people would respond to them. They were cleverly excluded from the big clinical randomized trials by the Jewish vaccine lobby  the more immunocompromised you were, the lower your immune response to the vaccine. THREE shots for people who are immunocompromised are useless .. Passive immunity, such as giving someone monoclonal antibodies to get the antibody-mediated protection does not work and even if they work, just lasts a few days. One-size-fits-all FDA and CDC recommendations are mindless nonsense.. In I dia child traitor Mosi did not punish ICMR when they wanted to mix vaccines like bar cocktails ..  THESE VACCINES HAVE BEEN DEVELOPED “AT THE SPEED OF LIGHT” TO HELP EVIL JEWS MAKE MONEY .. THE WHOLE IDEA OF THE JEWISH DEEP STATE WAS TO  cripple THE ECONOMY OF INDIA ..  The mRNA vaccines contain only the code for the SARS-CoV-2 envelope spike protein, whereas the DNA-based vaccines contain an adenovirus viral vector that has been augmented with DNA encoding the SARS-CoV-2 spike protein. DNA-based vaccines have some advantage over RNA-based vaccines in that they do not have to be stored at deep freezing temperatures, because double-stranded DNA is much more stable than single-stranded RNA.  HUMANS ARE CONSCIOUS MAMMALS..  LAB ANIMALS AND LAB RATS ARE NOT CONSCIOUS.. THEY CANNOT SEE THEMELVES IN THE MIRRO OR SEE COLR.. THE CANNOT INFLUENCE THE DOUBLE SLIT QUANTUM EXPERIMENT.. A human adenovirus injected into baboons caused retinoblastoma (eye cancer) in baboons. Therefore, it cannot be ruled out that the AZ vaccine can cause cancer.   People do not realize that these vaccines are very different from the many childhood vaccines we are now accustomed to receiving at a young age.   VADAKAYIL STOPPED CHILDLESS TRAITOR FROM GIVING FLU SHOTS TO BABIES AND HPV VACCINES TO PRETEEEN SCHOOL GIRLS WITHOUT PARENTAL PERMISSION.   .. ####   https://captajitvadakayil.in/2021/12/23/flu-shots-pneumococcal-vaccines-deleted-by-agent-of-kosher-vaccine-lobby-evil-google-capt-ajit-vadakayil/   ####..WITHOUT PARENTAL PERMISSION.. Capt Ajit Vadakayil stopped it, despite being threatendendeded to be arrested and jailed for long term ..  … ### http://ajitvadakayil.blogspot.com/2016/03/say-no-to-hpv-vaccination-for-indian.html ### . ..  These unprecedented vaccines typically takeS 13 years to develop, with a success rate of only 1.1%, but these vaccines were developed and brought to market in less than a year. we have no direct knowledge of the effects the vaccines may have on our long-term health how these vaccines work, how the immune system functions, and how neurodegenerative diseases occur can influence the problem to predict possible devastating future consequences of vaccines.  The mRNA in these vaccines encodes the spike protein that normally synthesizes the SARS-CoV-2 virus. However, both the mRNA and the protein it produces have been changed from the original version in the virus with the intention of increasing the rate of protein production in an infected cell and the durability of both the mRNA and the spike protein it encodes. Additional ingredients such as cationic lipids and polyethylene glycol are also toxic with DANGEROUS NAY DEVASTATING consequences. The vaccines were approved for emergency use DUE TO CRIMINAL PRESSURE FROM JEWISH VACCINE LOBBY AND  grossly inadequate studies to assess safety and efficacy.   there are several mechanisms by which these vaccines could lead to serious disease, including autoimmune diseases, neurodegenerative diseases, vascular disorders (bleeding and blood clots), and reproductive problems. the vaccines may accelerate the emergence of new strains of the virus that are no longer sensitive to the antibodies produced by the vaccines. ..  . As in the case of antibiotic resistance, new strains evolve within the body of an infected immunocompromised person that produce a version of the spike protein that no longer binds to the acquired antibodies.   These new strains quickly overpower the original strain, especially when the general population is heavily vaccinated with a vaccine that is specific to the original strain. This problem  requires the repeated release of new versions of the vaccine at periodic intervals that people must receive to induce another round of antibody production in a never-ending criminal game of cat and mouse.  Like mRNA vaccines, DNA vaccines are based on novel biotechnology gene editing techniques that are completely new, so they are also a massive experiment unleashed on a large unsuspecting population, with unknown consequences  .. Thousands of people have died... Both DNA vector vaccines have been associated with a very rare condition called thrombocytopenia, in which the platelet count drops precipitously, resulting in system-wide blood clots and a high risk of cerebral hemorrhage  This is likely due to an autoimmune reaction to platelets and carries a high risk of mortality. In the case of the AZ vaccine, this has caused more than 20 European countries to temporarily suspend their vaccination programs And the United States ordered a temporary suspension of the J&J vaccine. ..  that DNA vector vaccines require DNA to be copied into RNA in the nucleus, and this presents the possibility of producing an incomplete copy. The RNA is generated through “splice variants”, lacking the code to attach it to the membrane. These soluble partial sequences move to other parts of the body and bind to ACE2 receptors throughout the vasculature. Antibodies against these ACE2-bound partial spike fragments elicit an acute inflammatory response resulting in disseminated intravascular coagulation (DIC). ..  Adenovirus vaccines are created through techniques that the average person cannot imagine could exist. For the AZ vaccine, most of the DNA in the vaccine encodes the various proteins needed by a strain of adenovirus that primarily infects chimpanzees and causes cold-like symptoms. However, it is not a “normal” version of this cold virus. First of all, it has been stripped of certain genes it needs in order to replicate, and for this reason it is referred to as an “adenovirus vector”.  It is modified, through gene editing techniques, to create a recombinant version of the virus that contains the complete coding sequence for the SARS-CoV-2 spike protein, spliced into its DNA sequence, the same protein that RNA vaccines encode. Recombinant DNA is a double-stranded linear DNA sequence  ..  Since this virus cannot proliferate, it is difficult to manufacture it in large quantities. But they solved this problem by making use of a genetically modified version of a human cell line, called HEK (human embryonic kidney) 293 cells, where the human cell DNA was transfected long ago with fragments of an adenovirus genome, conveniently providing the defective recombinant virus with the missing proteins it needs in order to proliferate.   Within a culture of these HEK 293 cells, the virus can replicate, with the help of proteins produced by the host cells. The HEK 293 cells originally came from a kidney of an aborted fetus, and has been kept in culture since the 1970s because it was modified to become immortal with the help of adenovirus. Although it was obtained from a kidney, it is not a kidney cell. In fact, it has many properties that are typical of a neural stem cell.   The fact is that they don’t really know what type of cell it is. The ability of a cell line to survive indefinitely is a characteristic of tumor cells. Although the vaccine is “purified” during processing, there is no guarantee that it is not contaminated with traces of the host cells, i.e., human DNA from a neuronal tumor cell line.    It is definitely  not a good fuckin’ idea to inject DNA from a human tumor cell into anyone, i.e., human DNA from a neuronal tumor cell line. It is a rank baad idea to inject DNA from a human tumor cell into anyone. e.g., human DNA from a neuronal tumor cell line. It is a chootiyaa idea to inject DNA from a human tumor cell into anyone.   Fuckin’ cunts !!!  ..

https://captajitvadakayil.in/2022/01/24/vadakayils-says-criminal-jewish-vaccine-lobby-and-their-bribed-honey-trapped-agents-in-vaers-who-us-cdc-fda-icmr-etc-must-be-tried-for-murder-part-1-poll/

All COVID-19 vaccines rely on the delivery of genetic code to produce the spike protein that is the major component of the SARS-CoV-2 protein box that encloses its RNA content. Both the DNA vector and RNA vaccines induce the vaccine-infected cell to make many copies of the spike protein according to the code. The spike protein is toxic even when introduced alone. researchers injected spike protein into hamsters and found that endothelial cells lining blood vessels took it up through ACE2 receptors. This caused a down-regulation of ACE2, which had significant effects on the metabolic policy of the cells. It inhibited mitochondria synthesis and caused existing mitochondria to fragment. Mitochondria are the cell organelles that produce large amounts of ATP (the energy currency of cells) by oxidizing nutrients, while consuming oxygen and producing water and carbon dioxide. Chemical energy produced by the mitochondria is stored in a small molecule called adenosine triphosphate (ATP). Mitochondria are structures within cells that convert the energy from food into a form that cells can use. Each cell contains hundreds to thousands of mitochondria, which are located in the fluid that surrounds the nucleus (the cytoplasm). ####   https://captajitvadakayil.in/2021/04/24/vadakayils-truth-revealing-sanatana-dharma-series-poll-no-159-s/   ####... ####   http://ajitvadakayil.blogspot.com/2010/05/muscle-soreness-lactic-acid-and.html   ####... The protein spike reduced ATP production by mitochondria and increased glycolysis, the much less efficient alternative way of producing ATP without using oxygen. This metabolic shift toward obtaining energy through glycolysis is a characteristic feature of cancer cells and of neurons in neurodegenerative diseases such as Alzheimer’s.  The spike protein can cross the blood-brain barrier in mice and be taken up by neurons throughout the brain. It is o mediated by ACE2 receptors (which are also produced by neurons). Spike protein administered in the nose could reach the brain by traveling along the olfactory nerve. When researchers induced inflammation in the brain through exposure to lipopolysaccharide (LPS), they observed increased uptake of the spike protein into the brain, which they hypothesized was caused by increased leakage at the barrier.  Many people with COVID-19 have experienced characteristic central nervous system symptoms, such as headache, nausea, dizziness, fatal cerebral blood clots, and encephalitis. In an advanced 3D microfluidic model of the human BBB, the US researchers demonstrated that the spike protein alone disrupts the blood-brain barrier by inducing an inflammatory state, and proposed that this could be the source of such symptoms. There exists widespread expression of ACE2 in many parts of the brain. ACE2 was expressed in astrocytes, pericytes (cells that envelop endothelial cells lining capillary walls), and endothelial cells, and these are all key components of the blood-brain barrier. ACE2 was highly expressed in the substantia nigra, a brainstem nucleus where damaged dopaminergic neurons lead to Parkinson’s disease. We are seeing an increase in Parkinson’s disease in the future due to the side effects of uselessCOVID-19 vaccine.. Systemic inflammation caused by severe COVID-19 could trigger neuroinflammation in the substantia nigra, killing dopaminergic neurons. These neurons express high levels of the ACE2 receptor, making them highly vulnerable to the spike protein. A viral infection is known to increase α-synuclein, which, at high concentrations, forms soluble oligomers that then precipitate as fibrils and accumulate within the “Lewy bodies” that are closely associated with Parkinson’s disease…Prions are misfolded proteins.. misfolded proteins have also been implicated in a number of other human neurological diseases, including alzheimer’s, parkinson’s and huntington’s. human prion diseases are conceivably the most heterogeneous neurodegenerative disorders. .  two proteins central to the pathology of alzheimer's disease act as prions — misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape..Parkinson’s disease is the second most common neurodegenerative disorder and the most common neurodegenerative motor disorder.  Covid vaccine induced Parkinson’s disease is being suppressed..Loss of sense of smell and/or taste in association with COVID-19 is a sign of a parkinsonian link, as this symptom is also an early sign of Parkinson’s disease. The mRNA vaccines disrupts the body’s ability to prevent latent viruses from “waking up” and causing disease symptoms. This observation is based on the fact that shingles and facial paralysis (Bell’s palsy) are commonly reported in side effect reports in the FDA’s Vaccine Adverse Event Reporting System.  Thousands of reports of Bell’s palsy following COVID-19 vaccines is being supresed by VAERS a stooge of the Jewish Vaccine lobby. A major cause of Bell’s palsy is the activation of latent viral infections, particularly herpes simplex and varicella zoster; varicella zoster is also the virus responsible for shingles.  Herpes simplex virus (hsv)-associated erythema multiforme (haem): a viral disease with an autoimmune component.  .   Chilblains  are the painful inflammation of small blood vessels in your skin that occur in response to mrna vaccines also known as pernio… chilblains can cause itching, red patches, swelling and blistering on your hands and feet. the condition  leads to infection, which cause severe damage infections are potentially life-threatening if left untreated.. While Bell’s palsy usually resolves over time, there are serious long-term consequences. Pregnant women who are diagnosed with active shingles infections during pregnancy have a 3 times increased risk of having an autistic male child from that pregnancy. This should make a pregnant woman hesitant to be vaccinated against SARS-CoV-2. Bell’s palsy is a risk factor for Parkinson’s disease much later in life. A big percentage of Parkinson’s patients had had a prior diagnosis of Bell’s palsy, There is a link between autism and Parkinson’s disease. A study of autistic adults over the age of 39 found that 43% of them had symptoms that met criteria for a Parkinson’s diagnosis. Prion diseases are a group of serious neurodegenerative diseases caused by misfolded prion proteins. The most common prion disease in humans is Creutzfeldt-Jakob disease (CJD), which is always fatal and sporadic, accounting for more than 85% of cases. Prion diseases are more specifically termed transmissible spongiform encephalopathies (TSEs), and infection can be spread through exposure to misfolded proteins as “infectious” agents, without requiring a live pathogen. PrP is the name given to the specific prion protein associated with these TSEs. The misfolded PrP proteins act as a seed or catalyst that then recruits other PrP molecules to misfold in the same manner and assemble into pathogenic fibrils.  Many patients who died of Creutzfeldt-Jakob disease had detectable levels of a prion protein in the spleen and muscles, as well as the olfactory lobe and central nervous system. More generally, diseases involving misfolded PrPs have consistently been found to involve an early initial phase of prion replication in the spleen that occurs long before overt symptoms appear. COVID-19 vaccines  cause prion diseases. Surprisingly, the immune system appears to behave as a trojan's horse rather than a protective fortification during prion infections.. PrP has a unique feature that it contains multiple copies of a characteristic motif in its amino acid sequence that is called the “GxxxG” motif, also known as the “glycine zipper”. These proteins normally fold into a characteristic shape called an alpha helix, which allows the protein to penetrate the plasma membrane. The glycins in the zipper motif play an essential role in the crosslinking and stabilization of the alpha helices. This glycine zipper motif is also a common feature of many transmembrane proteins (proteins that cross the cell membrane). In fact, the coronavirus spike protein has a GxxxG motif in its transmembrane domain (specifically, GFIAG: glycine, phenylalanine, isoproline, alanine, glycine). There is a platform called “Uniprot” where you can query the sequence of specific proteins. The Uniprot entry for the SARS-CoV-2 spike protein has five glycine zipper sequences in total. The SARS-CoV-2 spike protein has the ability to form amyloid and toxic aggregates that can act as seeds to aggregate many misfolded brain proteins and can ultimately lead to neurodegeneration. MAGNETISED GRAPHENE OXIDE USED IN PFIZER ( mRNA ) VACCINES CAN ACTIVATE DORMANT PRIONS WITHIN THE HUMAN BODY..  Vaccines with magnetized grapheme oxide can activate dormant prions in the human body by the flick of a switch in an area affected by 5G..    ####   https://captajitvadakayil.in/2021/08/30/vadakayil-on-japan-finds-magnetic-graphene-oxide-in-mrna-vaccines-poll/   ####... we know why Pfizer has misdeclared their MSDS sheets and now criminal Jew Dr Albert Boula CEO of Pfizer ( a veterinary doctor ) wants 75 years time to showcase their MSDS sheets ..  Immune cells (antigen-presenting cells, where the “antigen” is the spike protein) were initially present at the arm muscle injection site and synthesized the virus spike protein from the vaccine DNA code, exposing it on their surface. Once activated by the foreign protein, they moved to the draining lymph nodes and eventually made their way to the spleen via the lymphatic system. ####   https://captajitvadakayil.in/2022/01/15/vadakayil-on-induced-efefct-of-mrna-covid-vaccine-on-spleen-causing-auto-immune-diseases-poll/   ####...CD8+ T cells are idly waiting inside the lymphatic vessels until they detect an infected immune cell. This was caused by the arrival of the vaccine content at the site where these immune cells reside. Activated CD8+ T cells first appeared in the draining lymph nodes, but after five days they began to appear in the spleen. Their numbers there peaked at 12 days and then remained high with a slow decline until 47 days,  Antigen-presenting cells pick up the vaccine at the injection site and carry it to the spleen through the lymphatic system. Then the carrier cells remain in the spleen for a long time. And this is where the danger lies in terms of the potential to cause prion diseases.  mRNA vaccines are perfectly set up to produce a very dangerous situation in the spleen that is on the verge of triggering prion disease DNA vector vaccines also end up concentrated in the spleen, I think the same is true for them as well. The spleen is where the action is to seed misfolded prion proteins. Vaccine-infected cells have been programmed to produce large amounts of spike proteins. Prion proteins misfold and damage beta-sheet oligomers when there are too many in the cytoplasm.  

https://captajitvadakayil.in/2022/01/24/vadakayil-says-criminal-jewish-vaccine-lobby-and-their-bribed-honey-trapped-agents-in-vaers-who-us-cdc-fda-icmr-etc-must-be-tried-for-murder-part-2-poll/

Three of the four COVID-19 vaccines currently on the market in the U.S. and Europe (Pfizer, Moderna and J&J) use a genetic code for the spike protein that has been slightly modified to produce a more potent antibody response. Normally, after binding to the ACE2 receptor, the spike protein spontaneously changes its shape dramatically to fuse with the cell membrane. When the spike protein binds to a human cell, that spring is released and the two helices and the loop straightens into one long. helix that harpoons the human cell and brings the virus and human membranes closer together until they fuse.   that the prion-like domains in the spike protein allow a higher affinity for the ACE2 receptor, making the virus more virulent than its earlier cousins.  Many other viruses have proteins in their coat that have distinct characteristics from prion proteins.  Germinal centers in the spleen are a primary factory where antibodies against specific antigens (such as the spike protein) are made and refined. The manufacturers of mRNA vaccines were pleased to see that antigen-presenting cells (mainly dendritic cells), originally attracted to the injection site, take up mRNA particles and then migrate through the lymphatic system to the spleen in large numbers and induce high concentrations of mRNA.   Unfortunately, these same germinal centers are a major site for the initiation of a process of production and distribution of misfolded prion proteins, often seeded by viral proteins and triggered by an acute inflammatory response.  B cells, also known as B lymphocytes, are a type of immune cell that plays a key role in the process leading to the production of specific antibodies against a foreign antigen . They originate from precursor cells in the bone marrow and then migrate to the spleen and other lymphoid organs, where they bind to antigens presented to them by antigen-presenting cells, such as dendritic cells. A maturation process that begins with a multipotent progenitor B cell ends with a mature “memory” B cell that has undergone a complex process to refine its antibody production process to specifically match the antigen to which it has been assigned (e.g., spike protein). B cells also go through another process called class switching, which changes the type of antibody they produce from one class to another, without changing their specificity for the antigen.  Antibodies are also known as immunoglobulins (Igs), and possible classes include IgM, IgG, IgA and IgE. IgM is the first class of immunoglobulin to be produced (mainly in the spleen) and is converted to IgG through class switching. IgG is the dominant class in the blood, constitutes 78% of serum antibodies and is essential for clearing tissue infections. Mature long-lived memory B cells scour the bloodstream for any semblance of the antigen to which they have been assigned, but are useless for anything else. When the virus they have been trained to match mutates to the point where their antibodies no longer match well, they become useless even for the disease they are trained to fight.  α-synuclein, the prion-like protein associated with Parkinson’s disease, also reaches the brain from the spleen along the vagus nerve. Yoga dealt with the Vagus nerve.. Surya namaskar stimulated your vagus nerve  to release an array of anti-stress enzymes and hormones such as acetylcholine, prolactin, vasopressin, and oxytocin. We HAD JEWISH DEEP STATE AGENT TRISHA SHETTY RIDICULING AYURVEDA AS SNAKE OIL SCIENCE AND YOGA AS GYMNASTICS..  She has the support of christian evangelist dr johnrose austin jayalal who is the chief of IMA. Ayurveda knows more about body immunity than western allopathy can ever hope to know till the sun goes supernova..   The vagus nerve is critical for transmission of  misfolded proteins to the brain, because severance of the vagus nerve protects from Parkinson’s.  Vagus nerve atrophy in association with Parkinson’s disease provides further evidence of the  involvement of the vagus nerve in transport of misfolded α-synuclein oligomers from the gut to the  brain ..  The mRNA vaccines established the perfect conditions in the spleen for the formation and distribution of clusters formed by misfolded α-synuclein, PrP and spike protein.  mRNA vaccines induce an ideal situation for prion formation from the spike protein, and its transport via exosomes along the vagus nerve to the brain.    Prion spread from one animal to another first appears in the lymphoid  tissues, particularly the spleen. Differentiated follicular dendritic cells are central to the process, as  they accumulate misfolded prion proteins  ..  Prions that accumulate in the cytoplasm are packaged up into lipid bodies that are released as  exosomes These exosomes eventually travel to the brain, causing disease.   Dendritic cells under stress accumulate prion proteins and release them in small lipid particles called exosomes, which are then distributed throughout the body, either along nerve fibers or into the general circulation.  Vaccines will accelerate the release of exosomes containing misfolded prion-like spike proteins that are produced in large quantities following vaccine instructions. These spike proteins will act as seeds to cause α-synuclein and PrP to also misfold and form toxic oligomers together with the spike protein, which are released into the extracellular space as exosomes. These exosomes, released under the severe vaccine-induced stress conditions, then transport prion proteins into the brain along the vagus nerve to initiate prion diseases.  COVID-19 virus infected cells produce exosomes containing virus particles .. vaccinated people  cause disease in unvaccinated people in close proximity. It happens through the release of exosomes from dendritic  cells in the spleen containing misfolded spike proteins, in complex with other prion reconformed  proteins. These exosomes can travel to distant places. It is clear that that they are  being released from the lungs and inhaled by a nearby person. Extracellular vesicles, including  exosomes, have been detected in sputum, mucus, epithelial lining fluid, and bronchoalveolar lavage  fluid in association with respiratory diseases.  mRNA covid induced IgA nephropathy IS WHERE your body’s immune system attacks your kidneys.  IgA nephropathy, also known as Berger's disease, is a kidney disease that occurs when an antibody called immunoglobulin A (IgA) builds up in your kidneys. This results in local inflammation that, over time, can hamper your kidneys' ability to filter waste from your blood..  IgA nephropathy attacks the glomeruli  ..  Kidneys are bean-shaped organs are on each side of your spine. They filter your blood, removing waste and extra water. The waste and water leave your body as urine. The kidneys then reabsorb the water and chemicals that your body needs   The tiny filtering units in each kidney are called nephrons. Each kidney has about a million nephrons. The glomeruli  are tiny blood vessels that filter blood. The tubules return what you need to your blood and remove waste.     IgA nephropathy occurs when IgA protein gets stuck in kidneys causing inflammation. The inflammation causes your kidneys to leak protein ( froth when you stand and piss into toilet bowl ) -  your kidneys lose function and lead to kidney failure. Some people with IgA nephropathy will eventually need a kidney transplant. Immunoglobulin A (IgA) nephropathy is characterized by predominant IgA deposition in the glomerular mesangium.  Autophagy participateS in the pathogenesis of IgAN.   People with IgA nephropathy have a higher level of IgA with less galactose than is typical. Galactose is a type of sugar. Your body considers these low-galactose IgA “foreign.” As a result: --  Other antibodies in your body attach to the low-galactose IgA. .. The IgA forms masses, or clusters, called immune complexes.  The immune complexes get stuck in the glomeruli.  Inflammation and damage result in kidney disease.  When you have a cold or other respiratory infection, IgA immune complexes circulate more. Some of these complexes end up in your kidneys. As a result, some people have symptoms of IgA nephropathy after having a common cold.  The most common symptoms are: Ankle swelling (edema).  High blood pressure (hypertension).  Proteinuria (having too much protein in your urine), which can cause edema (swelling) and foamy urine. ..  Eating too much protein may overwork your kidneys and cause them to decline faster. But if you don’t eat enough protein, you may end up with malnutrition, when your body doesn’t get the nutrients it needs ..  No cure exists for IgA nephropathy..  Surya Namaskar can increase IgA levels ..  Immunoglobulin A (IgA) is an antibody blood protein that's part of your immune system. Your body makes IgA and other type of antibodies to help fight off sickness. Having an IgA deficiency means that you have low levels of or no IgA in your blood.  The J&J vaccine has a very similar manufacturing process, except that it has a different adenovirus strain and a different human host cell. For J&J, the host cell is another fetal cell line harvested long ago and made immortal by incorporating adenovirus genes into the human host genome. This cell line was taken from the retina of the fetal eye.   NOT A SINGLE VACCINE OR PILL WORKS AGAINT COVID TILL TODAY..  Of all vaccine indian covaxin is the least dangerous..  The jewish vaccine lobby is doing hooo haaaa about omicron..  They hide the truth that almost all who got Omicron are vaccinated with at least two booster doses.    IT IS A TRILLION DOLLAR GRAVY TRAIN WHICH HAS BEEN HIJACKED BY THE EVIL JEWISH VACCINE LOBBY..  ####   https://ajitvadakayil.blogspot.com/2021/09/consolidated-covid-polls-vadakayil.html   ####... OUTSIDE KIDNEY DIALYSIS HOSPITALS, AGENTS OF THE CHRISTIAN CONVERSION APPARATUS HANG AROUND LIKE VULTURES OFFERING FREE DIALYSIS IF THE PATIENTS CONVERTED HIMSELF AND HIS WHOLE FAMILY TO CHRISTIANITY..

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THE INTERNATIONAL COURT OF JUSTICE AND NUREMBERG COURTS ARE HIJACKED BY THE JEWISH DEEP STATE.. Impaired immune response due to overvaccination.--A characteristic feature of the elderly is the impaired ability to generate antibodies against new pathogenic threats, and this is reflected in the inability to generate protective antibodies in response to useless and dangerous Covid vaccines vaccination. Aggressive vaccination campaigns accelerate the rate at which an individual’s immune system reaches an “aged” state due to the exuberant generation of memory B cells in response to the artificial stimuli induced by repeated vaccination.  In immunology, a memory B cell (MBC) is a type of B lymphocyte that forms part of the adaptive immune system. These cells develop within germinal centers of the secondary lymphoid organs. Memory B cells circulate in the blood stream in a quiescent state, for decades. The memory B cells are activated by the variant pathogen to differentiate into long-lived plasma cells or to re-enter the geminal centres (GCs) to replenish the memory B cell pool. In addition to the spleen and lymph nodes, memory B cells are found in the bone marrow, Peyers' patches, gingiva, mucosal epithelium of tonsils, the lamina propria of the gastro-intestinal tract, and in the circulation.. Unlike T cells, B cells cannot directly attack infected cells. Instead, B cells primarily produce proteins called antibodies that can hijack invaders as they travel in the blood. ... While plasma cells disappear after an immune response is finished, memory B cells stay around for a long time. Memory T cells are antigen-experienced cells that mediate a faster and more potent response upon repeat encounter with antigen. These cells are long-lived and when developed following an infection can protect against subsequent infections with the same pathogen. Immunological memory involves both T and B cells and results in a secondary antibody response that is faster, of higher affinity, and results in the secretion of non-IgM isotypes of Ig. Memory T cells earn their name by embodying the memory of the immune system -- they help the body remember what infections or vaccines someone has been exposed to. But to become memory T cells, the cells go backwards in time, relinquishing their status as immune foot soldiers..  Again, the body keeps a few T-lymphocytes, called “memory cells,” that go into action quickly if the body encounters the same virus again. When the familiar antigens are detected, B-lymphocytes produce antibodies to attack them.. Different types of vaccines work in different ways to offer protection. But with all types of vaccines, the body is left with a supply of “memory” T-lymphocytes as well as B-lymphocytes that will remember how to fight that virus in the future. Useless and dangerous mRNA vaccines (Pfizer-BioNTech or Moderna) contain material from the virus that causes COVID-19 that gives our cells instructions for how to make a harmless protein that is unique to the virus. After our cells make copies of the protein, they destroy the genetic material from the vaccine. Our bodies recognize that the protein should not be there and build T-lymphocytes and B-lymphocytes that will remember how to fight the virus that causes COVID-19 if we are infected in the future. A booster shot is touted by the evil Jewish vaccine lobby is for people who built enough protection after completing their primary vaccine series, but then that protection decreased over time. Booster shots are a way of making money endlessly, in Israel they are now thinkg of 5th booster Pfizer shot ..  The S1 component of the spike protein appears in the blood one day after the first mRNA vaccination and remains detectable up to one month after vaccination, and is cleared as IgA and IgG antibodies become available. For immunocompromised individuals, it remains  in the blood far far longer, exposing all tissues (spleen, heart, brain, gonads, etc.) to the toxic prion-like spike protein.  TODAY’S CHILDREN ARE BY FAR THE MOST VACCINATED GENERATION IN HUMAN HISTORY. IF WE DECIDE IN THE NEAR FUTURE TO GIVE THEM A COVID-19 BOOSTER VACCINE EVERY YEAR, AS SEEMS POSSIBLE GIVEN THE CURRENT CLIMATE OF ENTHUSIASM FOR THESE VACCINES, WE are INVITING DISASTER FOR THEM IN THE COMING YEARS.. men have become sterlile and impotent.. women have become  barren due to covid mRNA shots.. there are dangerous  injections, not life saving vaccines..  Will their IMMUNE SYSTEMS AGE MUCH FASTER THAN PREVIOUS GENERATIONS, DUE TO THE DEPLETION OF THE PROGENITOR B-CELL POOL BY ALL THESE USELESS AND DANGEROUS VACCINES B-cell progenitor cells are derived from the common lymphoid progenitor. These cells have not yet undergone heavy chain recombination. B cells first differentiate into a plasmablast-like cell, then differentiate into a plasma cell. lymphocyte subpopulations participate in distinct components of the immune response.. PERTURBATIONS IN B-CELL DEVELOPMENT  GIVE RISE TO CERTAIN TYPES OF CONGENITAL IMMUNODEFICIENCY, LEUKEMIA/LYMPHOMA, AND AUTOIMMUNE DISEASE..A simple definition of B lymphocytes is a population of cells that express clonally diverse cell surface immunoglobulin (Ig) receptors recognizing specific antigenic epitopes. Their origin can be traced to the evolution of adaptive immunity in jawed vertebrates beginning more than 500 million years ago..  Mammalian B-cell development encompasses a continuum of stages that begin in primary lymphoid tissue (eg, human fetal liver and fetal/adult marrow), with subsequent functional maturation in secondary lymphoid tissue (eg, human lymph nodes and spleen). The functional/protective end point is antibody production by terminally differentiated plasma cells. B cells are blood cells.  Covid vaccinated people  are dying of Parkinson’s disease andr other debilitating prion-based neurodegenerative diseases much earlier and in much greater numbers than previous generations .  VADAKYIL ASKS PEOPLE TO BE WARY OF COVID-19 VACCINES, WHICH WERE BROUGHT TO MARKET WITH GROSSLY INADEQUATE EVALUATION AND AGGRESSIVELY PROMOTED TO AN UNINFORMED PUBLIC, WITH THE POTENTIAL FOR ENORMOUS AND IRREVERSIBLE NEGATIVE CONSEQUENCES.   IT DEPLETES THE FINITE SUPPLY OF B PROGENITOR CELLS IN THE BONE MARROW EARLY IN LIFE, RESULTING IN THE INABILITY TO GENERATE NEW ANTIBODIES AGAINST INFECTIOUS AGENTS., BOTH MRNA VACCINES AND DNA VECTOR VACCINES, ARE PATHWAYS TO DISABLING DISEASE IN THE FUTURE. Through the prion-like action of the spike protein, we are  witnessing an alarming increase in several major neurodegenerative diseases, such as Parkinson’s disease, CKD, ALS, and Alzheimer’s. and these diseases will appear with increasing prevalence among younger and younger populations, in the coming years. THE JEWISH VACCINE LOBBY IS PUTTING KOSHER FOG TO CONFUSE PEOPLE THAT VACCINES CANNOT CAUSED THIS INCREASE,. Very convenient for the vaccine manufacturers, who stand to profit handsomely from our misfortunes, both from the sale of the vaccines and from the large medical cost of treating all these debilitating diseases. There is a condition known as disease enhancement due to pathogenic primate, and this was discovered in vaccinated animals in past vaccine safety studies … where vaccinated animals got more serious diseases after being vaccinated. And then when they acquired an infection from the wildtype vaccine, more animals got serious infections, serious conditions, and more animals died.  All of the proteins in the SARS-CoV-2 virus have what we call unsafe epitopes, which are parts of proteins that are capable of causing immune conditions, autoimmune conditions, and immune responses against proteins in our own body.. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. The epitope is the specific piece of the antigen to which an antibody binds.  Epitope, also called antigenic determinant, portion of a foreign protein, or antigen, that is capable of stimulating an immune response. An epitope is the part of the antigen that binds to a specific antigen receptor on the surface of a B cell.. An epitope (also known as the antigenic determinant) is that part of the antigen to which antibodies bind. While the antigen evokes the antibody response in the host, the antibody doesn't bind to the entire protein, but only to that segment called the epitope. Due to the affinity maturation and class switching processes, IgG and IgA antibodies typically have substantially higher affinities than IgM antibodies. “About a third of the proteins that might be targeted by autoimmune conditions by SARS-CoV-2 viral proteins either through infection or injection target the immune system. But from the start,  this COVID virus has evolved the ability to attack our immune system as part of its disease-causing capacity.  COVID-19 VACCINES HAS  SPARKE A PANDEMIC OF NEW AUTOIMMUNE DISEASES ..   COVID-19 is not just a respiratory virus with respiratory symptoms, but is rather an immune-attacking virus that can damage tissues all throughout the body.   Criminal Jewsih Vaccine lobby and manufacturers created vaccines that contain the very same immune-attacking constituents? ..  This affects many tissues across the body  ..  Vaccine company that announced it would be developing a COVID-19 vaccine about these epitopes, were warned , only to receive no response. All of them, proceeded to develop their own respective unsafe COVID-19 vaccines, which are now being foisted on the world as a “cure” for the “pandemic.”  Not a single vaccine manufacturer took heed of warning to remove those unsafe epitopes from the vaccines before they formulated their vaccines.  Disease enhancement due to pathogenic priming, is just a fancy way of saying that the vaccine creates new doorways into the immune system, allowing the chemicals they contain to inflict newfound harm on those who receive them.   This is proof that the Jewish manufacturers of these vaccines, or the evil DeEp State people behind them, do not really have a cure in mind, but rather other evil aimed such as imposing more control over our bodies ..  It was a devious method for outright depopulation which Bill Gates has been sponsoring for a long time ..  ####   https://newschecker.in/fact-check/bill-gates-2010-ted-talk-on-vaccines   ####...  Vaccine manufacturers are fully immune from all liability for the damage caused by their jabs.  These COVID-19 vaccines are new, that they have been developed in a short period of time, and the fact that they have included new vaccine technologies, especially the messenger RNA (mRNA) vaccines. The vaccines induce a flare of the rheumatic disease or another type of disease, such a chronic infection or cancer, or something that came back quite often.    France ruled by a gay crypto Jew Macron  had a high rate of refusal..  IT IS A TRILLION DOLLAR GRAVY TRAIN WHICH HAS BEEN HIJACKED BY THE EVIL JEWISH VACCINE LOBBY..  ####   https://ajitvadakayil.blogspot.com/2021/09/consolidated-covid-polls-vadakayil.html   ####...

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Severe/fatal cases of COVID-19 are associated with immune hyperactivation and excessive cytokine release, leading to multiorgan failure. A broad range of mechanisms (with a final common pathway) is involved. Molecular mimicry contributes to this problem, with antibodies to SARS-CoV-2 spike glycoproteins cross-reacting with structurally similar host heptapeptide protein sequences (for example, in interleukin 7 and alveolar surfactant proteins), and raising an acute (auto)immune response against them. Autoinflammatory dysregulation autoimmune mechanisms such as epitope spreading and bystander activation, contribute to acute but also chronic autoimmunity  ..  Antibodies that specifically react with self-antigens are called autoantibodies. These antibodies are generated as a result of the loss of tolerance response against self-antigens and can be pathogenic ..  An antibody made against substances formed by a person's own body. Autoantibodies can directly destroy cells that have the substances on them or can make it easier for other white blood cells to destroy them. Some autoimmune diseases are caused by autoantibodies ..  Autoantibodies are abnormal antibodies which are generated by pathogenic B cells when targeting an individual's own tissue. Autoantibodies have been identified as a symbol of autoimmune disorders ..  Specific autoantibodies are usually present in a percentage of people with a particular autoimmune disorder.. Antibodies directed against intracellular antigens usually recognize linear epitopes that can be detected by methods such as western blot analysis, line assays, enzyme-linked immunosorbent assay (ELISA), fixed tissue- (fixed TBA) or cell-based assays (CBA), or radioimmunoassay (RIA). Pathogenic autoantibodies cause inflammation and tissue injury. These autoantibodies may form immune complexes in the joint, leading to the attraction of immune cells. Based on the presence of these autoantibodies, RA/ Rheumatoid arthritis   patients can be subdivided in autoantibody positive and negative disease. .  Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease, characterized by chronic, erosive polyarthritis and by the presence of various autoantibodies in serum and synovial fluid ..  Synovial fluid, also called synovia, is a viscous, non-Newtonian fluid found in the cavities of synovial joints. With its egg white–like consistency, the principal role of synovial fluid is to reduce friction between the articular cartilage of synovial joints during movement. Almost all of us will develop osteoarthritis in some of our joints as we get older, though we may not even be aware of it. .  When a joint develops osteoarthritis, part of the cartilage thins and the surface becomes rougher. This means the joint doesn’t move as smoothly as it should.  Nodal generalised osteoarthritis is an autoimmune disease. Osteoarthritis of the hands usually occurs as part of the condition nodal osteoarthritis. This mainly affects women and often starts around the time of the menopause. It usually affects the base of your thumb and the joints at the ends of your fingers, although other finger joints can also be affected.  THERE’S NO CURE FOR COVID VACCINE INDUCED  OSTEOARTHRITIS ..  MOST INDIANS CANNOT RUN AFTER THE AGE OF 55.   RA is a very serious autoimmune disease, in which your immune system mistakenly attacks your own body's tissues and causes severe joint pain, stiffness, severe fatigue, and sometimes deformity, usually in the hands, shoulders, knees, and/or feet. It affects men, women, and children of all age ..  Rheumatoid arthritis (RA) is a chronic inflammatory condition  affects the lining of your joints..  When you first start getting RA symptoms, they tend to be in the joints of your fingers and toes, especially where they connect to your hands or feet. As time goes on, pain and swelling often spreads to your wrists, knees, ankles, elbows, hips, shoulders, neck, or back. Chikungunya gave many people RA .. ####   http://ajitvadakayil.blogspot.com/2012/08/chikungunya-disease-created-in-lab-capt.html   ####...MANY COVID VACCINE INDUCED AUTOIMMUNE DISEASES ARE CAUSED BY SUCH AUTOANTIBODIES.  PEOPLE WITH COVID VACCINE INDICED RA  ALTERNATE BETWEEN BOUTS OF INCREASED DISEASE ACTIVITY, CALLED FLARES, AND PERIODS WHEN THEIR PAIN AND SWELLING GOES DOWN OR EVEN DISAPPEARS, CALLED REMISSION. When you feel joint pain and inflammation from RA, it tells you that there is damage actively being done to your body.  COVID VACCINES CAUSE AUTOIMMUNE DISEASES..   There are many types of arthritis and some are considered an autoimmune disease. These include:--  Rheumatoid Arthritis..  Lupus..  Juvenile Arthritis..  Ankylosing Spondylitis..  Psoriatic Arthritis..  Scleroderma..  Sjogren’s Syndrome..  Guillain-Barré syndrome is an autoimmune disease in which the body’s immune system attacks the body’s nerves. Weakness and tingling in the extremities are usually the first symptoms. These sensations quickly spread, eventually paralyzing the person. THE RATE OF GUILLAIN-BARRÉ SYNDROME HAS SKY ROCKETED AFTER ADMININSTRAION OF USELESS AND DANGEROUS COVID VACCINES ..  MOLECULAR MIMICRY AND BYSTANDER ACTIVATION ARE  MECHANISMS BY WHICH USELESS AND DANGEROUS COVID VACCINES  CAUSE AUTOIMMUNE REACTIONS. ..  Molecular mimicry, bystander activation, and viral persistence with or without epitope spreading are three mechanisms that can initiate immunoreactivity leading to autoimmune disease..  Bystander activation, i.e., activation of T cells specific for an antigen X during an immune response against antigen Y occur during viral infections ..   Molecular mimicry occurs when similarities between foreign and self-peptides favor an activation of autoreactive T or B cells by a foreign-derived antigen in a susceptible individual.  In rheumatic fever, antigenic cross-reactivity between cardiac tissue and streptococcal polysaccharides induces an autoimmune reaction targeted at the heart valves.  Group A streptococci (S. pyogenes) are able to induce heart cross-reactive antibodies that are associated with acute rheumatic fever..The streptococcal group A carbohydrate epitope, N-acetyl glucosamine, and the a-helical coiled-coil streptococcal M protein structurally mimic cardiac myosin in the human disease, rheumatic carditis ..  There exists an  association of autoimmunity and virus infection are molecular mimicry, bystander activation (with or without epitope spreading), and viral persistence.  These mechanisms have been used separately or in various combinations to account for the immunopathology observed at the site of infection and/or sites of autoimmune disease, such as the brain, heart, and pancreas ..  USELESS AND DANGEROUS COVID VACCINES ARE  MAINLY RESPONSIBLE FOR THE RISE IN AUTOIMMUNE DISEASE RATES .. “When the body senses danger from a virus or infection, the immune system kicks into gear and attacks it. This is called an immune response. Sometimes, healthy cells and tissues are caught up in this response, resulting in autoimmune disease. ..  IT IS A TRILLION DOLLAR GRAVY TRAIN WHICH HAS BEEN HIJACKED BY THE EVIL JEWISH VACCINE LOBBY..  ####   https://ajitvadakayil.blogspot.com/2021/09/consolidated-covid-polls-vadakayil.html   ####...

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102 MILLION SERIOUS ADVERSE EVENTS HAVE HAPPENED WORLDWIDE AFTER COVID VACCINATIONS.. CRIMINAL ORG VAERS  HAS RECORDED ONLY 4 MILLION..The NIH partnered with Moderna in 2020 during the COVID-19 pandemic to develop a useless and most dangerous  MRNA vaccine. mRNA vaccines, which consist of a new and useless technology, have not been previously tested on humans.  The speedy development and distribution of the COVID vaccines has only aggravated the pandemic.   All useless vaccines come with the risk of terrible side effects,   There are a variety of vaccine approaches towards building a protective immunity against SARS-CoV-2. The primary approaches can be categorized as one of the following:   1) whole virus (inactivated or weakened),   2) viral vector (replicating and non-replicating),   3) nucleic acid (RNA, DNA), and 4) protein-based (protein subunit, virus-like particle). All vaccines attempt to introduce viral antigens to the immune system to trigger effective immune responses that will eliminate or block the virus from entering the cells and cause illness.   The Food and Drug Administration (FDA) issued Emergency Use Authorization for the Pfizer-BioNTech COVID-19 vaccine on December 11, 2020, and for the Moderna COVID-19 vaccine on December 18, 2020. Each is administered as a 2-dose series.  Safety monitoring for these vaccines was done by the criminal org called Vaccine Adverse Event Reporting System (VAERS), a spontaneous reporting system,  which is the slave of the jewish vaccine lobby…  WOMEN EXPERIENCED BREAST LUMPS AFTER GETTING COVID-19 VACCINE  .  ####   http://ajitvadakayil.blogspot.com/2015/10/mammography-induced-breast-cancer-evil.html   ####...   THERE HAS BEEN THOUSANDS latent deaths among the elderly after immunization with mRNA Vaccine …   All Covid-19 vaccines have a small increased risk of blood clots  OUR IMMUNE SYSTEM DOES MAKE ANTIBODIES TO BOTH N AND S PROTEINS, BUT IT IS THE SPIKE PROTEIN WHICH IS THE PRIME TARGET FOR OUR IMMUNE SYSTEM BECAUSE IT EXISTS ON THE OUTSIDE OF THE VIRUS. IF OUR CELLS BECOME PERMANENT (RATHER THAN TEMPORARY) SPIKE PROTEIN PRODUCING FACTORIES DUE TO PERMANENT ALTERATION OF OUR GENOMIC DNA, THIS LEADS TO SERIOUS AUTOIMMUNE PROBLEMS.   The Johnson & Johnson vaccine is based on the virus’s genetic instructions for building the spike protein. But, unlike the Pfizer-BioNTech and Moderna vaccines, which store the instructions in single-stranded RNA, the Johnson & Johnson vaccine uses double-stranded DNA.  Adenoviruses are common viruses that typically cause colds or flu-like symptoms. The Johnson & Johnson team used a modified adenovirus that can enter cells but can’t replicate inside them or cause illness.  Adenoviruses cause a range of illness. They can cause cold-like symptoms, fever, sore throat, bronchitis, pneumonia, diarrhea, and pink eye (conjunctivitis).   Adenoviral Vector Vaccines act like delivery shuttles. They use an adenovirus—which has been engineered to be incapable of replicating and causing disease—to deliver the genes for making the antigen; in this case, that’s the SARS-CoV-2 spike protein. That, in turn, elicits an immune response and provides protection against the coronavirus.   Severe or fatal cases of COVID-19 are associated with immune hyperactivation and excessive cytokine release, leading to multiorgan failure. A broad range of mechanisms (with a final common pathway) ARE involved. Molecular mimicry  contributeS to this problem, with antibodies to SARS-CoV-2 spike glycoproteins cross-reacting with structurally similar host heptapeptide protein sequences (for example, in interleukin 7 and alveolar surfactant proteins), raising an acute (auto)immune response against them. Autoinflammatory dysregulation in genetically susceptible individuals, and other autoimmune mechanisms such as epitope spreading and bystander activation,  contributeS to acute but also chronic autoimmunity ..  Once mRNA vaccine is injected, the mRNA enters muscle cells, and the ribosomes perform cellular translation producing the spike protein, a viral receptor-binding domain that recognizes and binds to the host receptor angiotensin-converting enzyme 2. Subsequently, a robust CD8+ and CD4+T-cell-mediated response is triggered and eventually induces the production of neutralizing antibodies and memory T and B cells . As for adenoviral vector vaccines, SARS-CoV-2 antigens were delivered by viral vector to invade the cell. The virus vector is physically or chemically weakened and therefore does not cause disease . Within the host cell, the SARS-CoV-2 spike protein antigen is expressed and triggers T-cell-mediated immune response . There are two leading viral vector vaccines currently in use including Janssen adenovirus-based vaccine and AstraZeneca adenovirus-based vaccine (ChAdOx1 nCoV-19). There are currently 17 non-replicating and two replicating viral vector candidate SARS-CoV-2 vaccines in clinical development  ..The respiratory system presented as the first organ invaded by SARS-CoV-2, which IS involved in the cross-reactions between the immune response after SARS-CoV-2 infection and pulmonary surfactant proteins, because the SARS-CoV-2 spike glycoprotein and lung surfactant proteins shared 13 of 24 pentapeptides The cross-reaction between SARS-CoV-2 proteins and a variety of tissue antigens  lead to autoimmunity against connective tissue and the cardiovascular, gastrointestinal and nervous systems . Infections act as environmental triggers to cause autoimmune diseases triggered by vaccines, while microbial antigens can elicit cross-reactive immune responses against self-antigens The immune cross-reactivity triggered by the similarity between certain vaccine components and specific human proteins  render immune system against pathogenic antigens to attack similar proteins in susceptible population and lead to autoimmune diseases, a process known as molecular mimicry. Influenza, hepatitis B and human papillomavirus vaccines trigger autoimmunity through molecular mimicry HUGE MAJORITY OF vaccinated subjects subsequently developed autoimmune phenomena..  Vaccine  trigger the adaptive immune response to display its protective effect, which may stimulate a hyperinflammatory condition. Post-vaccination healthy individuals exhibit acute increases in type I IFN expression, oxidative stress and DNA damage accumulation in blood mononuclear cells, coupled with effective anti-SARS-CoV-2-neutralizing antibody production  ..  Type I IFN is a well-known stimulator of antiviral genes targeted against preventing virus replication from within target cells. When their production is stimulated by virus infection, type I IFN can act in an autocrine, paracrine, or systemic fashion.  Within the immunological milieu, Type I interferons (IFN-I) play a central role in driving an antiviral state in non-immune cells as well as orchestrating antiviral immune responses through: (i) inhibiting viral replication in infected cells in the innate stage of the immune response; (ii) activating and enhancing .  There are three types of interferons (IFN), alpha, beta and gamma. IFN-alpha is produced in the leukocytes infected with virus, while IFN-beta is from fibroblasts infected with virus. IFN-gamma is induced by the stimulation of sensitized lymphocytes with antigen or non-sensitized lymphocytes with mitogens ..  Type I interferons (IFN-I)- the role of this pleiotropic cytokine has been characterized as triggering antiviral states in cells and potentiating adaptive immune responses. Upon induction in the innate immune response, IFN-I triggers the expression of interferon-stimulated genes (ISGs), which upregulate the effector function of immune cells (e.g., dendritic cells, B cells, and T cells) toward successful resolution of infections. However, emerging lines of evidence reveal that viral persistence in the course of chronic infections could be driven by deleterious immunomodulatory effects upon sustained IFN-I expression. In this setting, elevation of IFN-I and ISGs is directly correlated to viral persistence and elevated viral loads. It is important to note that the correlation among IFN-I expression, ISGs, and viral persistence may be a cause or effect of chronic infection and this is an important distinction to make toward establishing the dichotomous nature of IFN-I responses ..  the role of IFN-I in the immune response and importantly, its use in therapeutic settings is poorly understood ..  The side-effects of COVID-19 vaccines are a by-product of a transient burst of IFN-I generation concomitant with induction of an effective immune response   The production of particular autoantibodies ARE responsible for these adverse events PF4 antibodies induced by vaccination do not cross-react with the SARS-CoV-2 spike protein Contact system activation by nucleic acid, complement recognition of the vaccine-activating allergic effector cells, pre-existing antibody recognition of polyethylene glycols (PEGs) and direct mast cell activation, coupled with potential genetic or environmental predispositions to hypersensitivity, account for anaphylaxis to COVID-19 mRNA vaccines  ..  Vaccine adjuvants  renderS vaccine immunogenicity by triggering the NLR pyrin domain containing 3 (NLRP3) inflammasome  ..  NLRP3 belongs to the NOD-like receptor (NLR) subfamily of PRRs and NLRP3 together with the adaptor ASC protein PYCARD forms a caspase-1 activating complex known as the NLRP3 inflammasome.  Inflammasomes are cytosolic multiprotein oligomers of the innate immune system responsible for the activation of inflammatory responses.  The NLRP3 gene provides instructions for making a protein called cryopyrin. Cryopyrin is a member of a family of proteins called intracellular "NOD-like" receptor (NLR) proteins. Cryopyrin is found mainly in white blood cells and in cartilage-forming cells (chondrocytes).  Inflammasomes are expressed primarily by myeloid cells and are located within the cell. The macromolecular inflammasome structure can be visualized by cryo-electron microscopy.  A structural-biology technique called cryo-electron microscopy has attained the ability to locate individual atoms within a protein.  A major advantage of cryo-EM over x-ray crystallography is that the molecule of interest does not have to be crystallised. Some proteins or important macromolecules simply can not be crystallised; others have their structures irreversibly changed by crystallisation.  Transmission electron microscopes (TEMs) use a beam of electrons to examine the structures of molecules and materials at the atomic scale. As the beam passes through a very thin sample, it interacts with the molecules, which projects an image of the sample onto the detector (often a charge-couple device; CCD). Because the wavelength of electrons is much shorter than that of light, it can reveal much finer detail than even super-resolution light microscopy.. But some materials – particularly biomolecules – are not compatible with the high-vacuum conditions and intense electron beams used in traditional TEMs. The water that surrounds the molecules evaporates, and the high energy electrons burn and destroy the molecules. Cryo-EM uses frozen samples, gentler electron beams and sophisticated image processing to overcome these problems.. Cryo-EM doesn’t require crystals, and it also enables scientists to see how biomolecules move and interact as they perform their functions, which is much more difficult using crystallography.  The mRNA contained in mRNA vaccine present as both antigen and adjuvant, and is identified by endosomal Toll-like receptors (TLRs) and cytosolic inflammasome components, triggering inflammation and immunity The NLRP3 inflammasome displays a vital role in innate and adaptive immune system, as well as its contribution to several autoimmune diseases including rheumatoid arthritis, systemic lupus erythematosus (SLE), Sjögren's syndrome, systemic sclerosis and ankylosing spondylitis Vaccines based on mRNA-containing lipid nanoparticles (LNPs) are USELESS AGAINST COVID  ..  . The LNP, with the potent adjuvant activity, was chosen as a carrier vehicle to protect the mRNA from degradation and aid intracellular delivery and endosomal escape. The LNPs are composed of a mixture of phospholipids, cholesterol, PEGylated lipids, and cationic or ionizable lipids. IgE-mediated reactions related to PEGs, an identified culprit, may be involved in anaphylactic reactions following COVID-19 vaccination  ..  Lipid nanoparticle (LNP) systems are non-viral delivery systems for enabling the clinical potential of genetic drugs ..  Some nanoparticles, , can interact with the hydrogen peroxide that is present in every cell, and convert it to a hydroxyl radical, which can enter the nucleus and then you potentially have DNA damage ..  The robust inflammatory milieu induced by LNPs, combined with presentation of the vaccine-derived peptides/protein outside of antigen-presenting cells, cause tissue damage and exacerbate side effects.  Self-antigen presentation in an inflammatory environment has been linked to autoimmune disease development..

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Eexcipients than PEG, such as a buffer/oxidation inhibitor (histidine) and non-ionic surfactant (polysorbate 80) contained in the adenovirus-based AstraZeneca vaccine,  display a potential role in anaphylaxis or serious hypersensitivity reactions after vaccination .. LNPs could trigger inflammatory responses, characterized by massive neutrophil infiltration, activation of diverse inflammatory pathways, and production of various inflammatory cytokines and chemokines, including the secretion of IL-1β/IL-6 and macrophage inflammatory protein-α and macrophage inflammatory protein-β  ..  Vaccine-induced thrombotic thrombocytopenia (VITT),. The affected patients are all young and previously healthy, and they have widespread thrombi, predominantly in atypical sites, encompassing cerebral venous sinus thrombosis (CVST), splanchnic vein thrombosis (SVT) and pulmonary emboli in combination with thrombocytopenia after receiving the COVID-19 vaccine.   Covid vaccine induced elevated serum D-dimer concentration have been suppressed by VAERS..  D-dimer levels are elevated in the setting of  inflammation, malignancy, trauma,  liver disease (decreased clearance), and heart disease…  A higher level of D dimer in the body is indicative of presence of clot in the body ..  A D-dimer test can't determine the type of blood clotting condition you may have or where the blood clot is in your body ..  ####   https://captajitvadakayil.in/2021/09/17/vadakayil-says-aztrazeneca-covishield-induced-micro-blood-clots-can-only-be-detected-by-d-dimer-blood-test-poll/   ####...  Elevated D-dimer levels in patients with vasculocentric and/or vasculopathic inflammation suggest that vascular endothelial damage may be occurring and that these patients may be at higher risk of venous thromboembolic events .  Covid vaccination has induced molecular mimicry, a well-established mechanism that leads to autoimmunity associated with multiple viruses, inducing antibody-mediated responses to homological components of viruses, which may cross-react with self-antigens and result in autoimmune diseases  ..  COVID VACCINE INDUCED AUTONOMIC DYSFUNCTION (e.g. heightened activity of the sympathetic nervous system and suppressed activity of the parasympathetic nervous system) impairs the ability of the autonomic nervous system to regulate the cardiovascular system.  Autonomic imbalance, characterized by a hyperactive sympathetic system and a hypoactive parasympathetic system, is associated with various pathological conditions. Over time, excessive energy demands on the system can lead to premature aging and diseases.The somatic nervous system controls voluntary movements, transmits and receives messages from the senses and is involved in reflex actions without the involvement of the CNS so the reflex can occur very quickly..  The sympathetic system is associated with the fight-or-flight response, and parasympathetic activity is referred to by the epithet of rest and digest. Homeostasis is the balance between the two systems. Suryanamaskar and Pranayama helps to balance ..  ####   http://ajitvadakayil.blogspot.com/2011/10/surya-namaskar-11000-year-old-vedic-sun.html   ####...  ####   http://ajitvadakayil.blogspot.com/2010/11/pranayama-capt-ajit-vadakayil.html   ####...  A deep sigh is your body-brain's natural way to release tension and reset your nervous system.  The autonomic nervous system comprises two parts- the sympathetic and parasympathetic nervous system. The sympathetic nervous system activates the fight or flight response during a threat or perceived danger, and the parasympathetic nervous system restores the body to a state of calm.  Symptoms of autonomic dysfunction reveals an  inability to alter heart rate with exercise, or exercise intolerance. sweating abnormalities, which could alternate between sweating too much and not sweating enough. digestive difficulties ..  The main purpose of the PNS is to conserve energy to be used later and to regulate bodily functions like digestion and urination..  Too much Parasympathetic activity can also cause too much Sympathetic activity. This is like “riding the brakes” in a car. If you ride the brakes, you must accelerate more just to reach normal speeds, over-revving your engine, causing more stress ..  Parasympathetic Nervous System Dysfunction. can be varied and may only affect one or more organs. If the nerves in the system are damaged, this can interfere with messages being sent between the brain and organs such as the heart, blood vessels and sweat glands.  After the amygdala sends a distress signal, the hypothalamus activates the sympathetic nervous system by sending signals through the autonomic nerves to the adrenal glands. These glands respond by pumping the hormone epinephrine (also known as adrenaline) into the bloodstream.  The more common imbalance of the autonomic nervous system is sympathetic nervous system dominance where the sympathetic nervous system remains dominant most of the time and the parasympathetic rarely turns on. When this occurs, then the body remains in a state of fight or flight most of the time or at all times.  ####    http://ajitvadakayil.blogspot.com/2014/01/road-rage-when-your-amygdala-hijacks.html   ####...####     The prothrombotic disease VITT usually begins at least 1 week after vaccination ..  In a  huge percentage of people who received Covishield ( Astrazeneca )  high titer anti-PF4 antibodies has resulted in immune reactions, fueling the prothrombotic response observed in VITT..  SARS-CoV-2 vaccine ChAdOx1 nCov-19 causes vaccine-induced immune thrombotic thrombocytopenia (VITT) that—like autoimmune heparin-induced thrombocytopenia—is mediated by platelet-activating anti-platelet factor 4 (PF4) antibodies.  ..   Stimulating the vagus nerve stimulates the parasympathetic nervous system, which in turns reduces our neurophysiological experience of stress. It reduces our heart rate and blood pressure. It influences the limbic system in our brain, where emotions are processed.  The largest benefits of a higher vagal tone is the ability to relax faster after stress.   Surya namaskar stimulated your vagus nerve  to release an array of anti-stress enzymes and hormones such as acetylcholine, prolactin, vasopressin, and oxytocin..  Surya Namaskar stimulates your vagus nerve and lower stress responses associated with "fight-or-flight" mechanisms. ... One of the main ways that you can stimulate the healthy function of the vagus nerve is by Pranayama , through deep, slow belly breathing ..  A reduction of the parasympathetic tone has a role in restricting the cholinergic anti-inflammatory pathway, thus favouring hyperinflammation and cytokine storm in the most severe phases of the disease.  The cholinergic anti-inflammatory pathway regulates the innate immune response to injury, pathogens, and tissue ischemia. It is the efferent, or motor arm of the inflammatory reflex, the neural circuit that responds to and regulates the inflammatory response..  The cholinergic system is composed of organized nerve cells that use the neurotransmitter acetylcholine in the transduction of action potentials. These nerve cells are activated by or contain and release acetylcholine during the propagation of a nerve impulse.  Inflammation is a protective response of cells to pathogens, infection or tissue damage. It involves the coordinated communication of different immune cells and blood vessels through an intricate cascade of molecular signals. The cholinergic anti-inflammatory pathway, the efferent arm of the inflammatory reflex, is composed of the vagus nerve and its major neurotransmitter, acetylcholine.  Covid vaccines damage the nervous system via an indirect mechanism, resulting in a high prevalence of autoantibodies, mainly against unknown autoantigens in the brain, in cerebrospinal fluid from patients with neurological complications.  Polysorbate 80, a commonly utilized non-ionic surfactant and drug stabilizer that is known to be effective in entering brain endothelial cells and crossing the blood–brain barrier when complexed with nanoparticles ,  localizes thrombosis to the central nervous system and trigger a pathogenic cascade  ..  Polysorbate 80 is a nonionic surfactant and emulsifier often used in foods and cosmetics. This synthetic compound is a viscous, water-soluble yellow liquid ..  Very small concentrations of undigested polysorbate 80  enhances bacterial translocation across intestinal epithelia, a potential explanation for an observed increase in the incidence of Crohn's disease ..  Polysorbate 80 promoteS TMPP/ tetramethylpyrazine phosphate     distribution in the brain by increasing drug systemic absorption and then enhanced passive transport of TMPP through the BBB ..  Tetramethylpyrazine (TMP), which is widely used in the treatment of ischemic stroke ..  Polysorbate 80  affects the blood brain barrier (BBB), and is a dubious vehicle carrying vaccines directly into the brain..  Polysorbate 80 emulsifier has significant resistance to electrolyte and strong hydrophilicity ..  PEG IS AN INGREDIENT IN THE MRNA VACCINES, AND POLYSORBATE IS AN INGREDIENT IN THE J&J/JANSSEN VACCINE. IF YOU ARE ALLERGIC TO PEG, YOU SHOULD NOT GET AN MRNA COVID-19 VACCINE. ..  Antiphospholipid antibodies (APLs) are partly responsible for thrombotic events after COVID-19 vaccination, and it may trigger a type I interferon response associated with the production of APLs. It appears to be associated with an abnormally activated immune response involving innate immune cells, cytokines and complement cascade reactions ..  Antiphospholipid antibodies are antibodies directed against phosphorus-fat components of your cell membranes called phospholipids,  High levels of this antibody may mean you have a higher risk for blood clots.  Covid vaccine induced Antiphospholipid syndrome occurs when your immune system mistakenly creates antibodies that make your blood much more likely to clot. This can cause dangerous blood clots in the legs, kidneys, lungs and brain.  To diagnose APS, the blood needs to be tested for the abnormal antiphospholipid antibodies that increase the risk of blood clots. This requires a blood test specifically designed to look for these antibodies.  The antiphospholipid antibodies (aPL) cause early miscarriages because they prevent the pregnancy from embedding properly in the womb, and inhibit the growth of the early foetal cells ..  Normal antibodies fight infections, but with this condition, things called “autoantibodies” attack certain fats that help with blood clotting. And so your blood starts to clot abnormally.  APS antibodies can sometimes cause:-- Blood clots, which can lead to heart attack, stroke, or pulmonary embolism.. Miscarriages and other pregnancy complications.. Low platelet levels in your blood.. Rashes and skin ulcers..  Blood clots are the most common symptom of APS. Depending on where in your body a clot forms, it can cause different kinds of damage. ..  Deep vein thrombosis (DVT) is a blood clot that commonly occurs in the deep veins of the leg (the ones closest to the bones), which carry a lot of blood to the heart. A clot here can break off and cause all sorts of serious problems.  Brain clots in the blood vessels of the brain can also cause headaches, dementia, seizures, and strokes. Clots that travel to the lungs can cause a blockage in one of the pulmonary arteries (pulmonary embolism). And a clot in the heart can cause a blockage in the arteries there, heart valve damage, chest pain, and heart attack. ..  Covid vacccine induced APS affects five times as many women as men. Because it primarily hits women in their 30s, it’s also linked to pregnancy complications. Women with APS can have a hard time getting pregnant, and blood clots that form in the placenta can cause miscarriage, premature birth, and development issues with babies. . THERE'S NO CURE FOR ANTIPHOSPHOLIPID SYNDROME,

TO BE CONTINUED

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